2-aminooxazole derivatives as trpv1 antagonists useful for...

Details 2-aminooxazole derivatives as trpv1 antagonists useful for... 2-aminooxazole derivatives as trpv1 antagonists useful for...

C - Chemistry, Metallurgy

07

D

C07D 263/48 (2006.01) A61K 31/421 (2006.01) A61P 29/00 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2702976

Compounds of formula (I) wherein R1, R2, R4, and W are defined in the description are TRPV1 antagonists with CNS penetration. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

L'invention concerne des composés de formule (I) dans laquelle R1, R2, R4 et W, qui sont définis dans la description, sont des antagonistes de TRPV1 avec pénétration du système nerveux central. Des compositions comprenant de tels composés et des procédés de traitement des affections et des troubles utilisant de tels composés et compositions sont également révélés.

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