A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/24 (2006.01) A61K 31/13 (2006.01) A61K 31/71 (1990.01)
Patent
CA 2120234
2120234 9308120 PCTABS00021 The present invention provides a pharmaceutical system adapted to inhibit the growth of a mammalian cancer tumor or cell characterized by a chemotherapeutic agent selected from adriamycin and cisplatin in conjunction with an effective amount of a potentiating agent comprising a compound having formula (I), wherein R is C5-C20 alkyl, alkenyl or alkynyl. The present invention further provides a method of inhibiting the in vitro growth of a mammalian cancer tumor or cell comprising administering to the tumor or cell an amount of a chemotherapy agent selected from adriamycin and cisplatin effective to inhibit growth of the tumor or cell; and administering to the tumor or cell an amount of a potentiating agent comprising a compound having formula (II) wherein R is C5-C20 alkyl, alkenyl or alkynyl, in an amount effective to induce enhanced growth inhibition produced by the chemotherapy agent.
Borden Ladner Gervais Llp
Sphinx Pharmaceuticals Corporation
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