C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01) A61K 31/427 (2006.01) A61K 31/4427 (2006.01) A61P 3/10 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2681695
Provided are compounds of formula (I) that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes mellitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase or which can be treated by activating glucokinase.
La présente invention concerne des composés qui sont utiles dans le traitement et/ou la prévention de maladies provoquées par des niveaux déficients de l'activité de la glucokinase, telles que le diabète sucré. L'invention concerne également des procédés de traitement ou de prévention de maladies et de troubles caractérisés par une sous-activité de la glucokinase ou qui peuvent être traités en activant la glucokinase.
Aicher Thomas Daniel
Boyd Steven Armen
Chicarelli Mark Joseph
Condroski Kevin Ronald
Hinklin Ronald Jay
Array Biopharma Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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