2-aminopyridine compounds useful as beta-secretase...

C - Chemistry – Metallurgy – 07 – D

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C07D 211/72 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2585279

The present invention is directed to 2-aminopyridine compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

L'invention concerne des composés de 2-aminopyridine qui sont des inhibiteurs de l'enzyme bêta-secrétase et utiles dans le traitement de maladies dans lesquelles ladite enzyme est impliquées, telles que la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques comprenant ces composés et l'utilisation de ces composés et compositions dans le traitement de telles maladies dans lesquelles l'enzyme bêta-secrétase est impliquée.

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