C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) C07D 213/75 (2006.01) C07D 401/14 (2006.01) C07D 475/04 (2006.01)
Patent
CA 2512646
The present invention provides substituted 2-aminopyridines of formula (I), wherein R1, A1, W, X, and Y are as defined in the specification, useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (Cdk4).
La présente invention concerne des 2-aminopyridines substituées correspondant à la formule (I), dans laquelle R?1¿, A?1¿, W, X et Y correspondent à la définition donnée dans la description, qui sont utiles dans le traitement de troubles se traduisant par une prolifération cellulaire. Ces nouveaux composés constituent de puissants inhibiteurs des kinases cyclines-dépendantes 4 (Cdk4).
Biwersi Cathlin Marie
Mcnamara Dennis Joseph
Repine Joseph Thomas
Toogood Peter Laurence
Vanderwel Scott Norman
Torys Llp
Warner-Lambert Company Llc
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