C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/10 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 213/73 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/10 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 413/10 (2006.01) C07D 451/06 (2006.01) C07D 453/02 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01)
Patent
CA 2296313
The present invention relates to 2-aminopyridine derivatives of formula (I) wherein G, R1 and R2 are defined as in the specification, that exhibit activity as nitric oxide synthase (NOS) inhibitors, to pharmaceutical compositions containing them and to their use in the treatment and prevention of central nervous system and other disorders.
La présente invention concerne des dérivés de 2-aminopyridine correspondant à la formule (I) dans laquelle G, R<1> et R<2> sont tels que définis dans la description,. Ces dérivés possèdent une activité en tant qu'inhibiteurs des monoxyde d'azote synthétases (NOS). L'invention concerne également des compositions pharmaceutiques contenant ces dérivés, ainsi que l'utilisation de ces compositions dans le traitement et la prévention de maladies du système nerveux central et autres troubles.
Pfizer Products Inc.
Smart & Biggar
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