2-aminopyrimidine-4-carboxamide, their preparation and their...

Details 2-aminopyrimidine-4-carboxamide, their preparation and their... 2-aminopyrimidine-4-carboxamide, their preparation and their...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2072434

- 28 - ABSTRACT A compound which is a 2-aminopyrimidine carboxamide derivative represented by formula (I) Image (I) in which X represents hydrogen, fluorine, chlorine, methyl, 1- methylethyl or methoxy, with the proviso that more than one substituent X may be present in which case each X may be the same or different, n represents 2 or 3, m represents 1, in which case p represents 1, or else m represents 0, in which case p represents 2, q represents 0 or 1, and R1 represents a hydrogen atom; or a pharmaceutically acceptable acid addition salt thereof. A compound of formula (I) has .alpha.1-adrenergic receptor antagonist activity and is useful as a therapeutic substance.

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