2-aminopyrimidinone derivatives

Details 2-aminopyrimidinone derivatives 2-aminopyrimidinone derivatives

C - Chemistry, Metallurgy

07

D

167/218, 260/255

C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2007200

2-Amino-pyrimidininone derivatives possessing serotonin-antagonistic and anti-histaminic properties having the formula: (see fig. I) are described. Compositions containing these compounds as the active ingredient are also described. Method of treating subjects suffering from diseases and/or disorders associated with the release of neurotransmitters, in particular, a method of treating subjects suffering from sleep disorders with 2-aminopyrimidinone derivatives substituted with a 4-bis(aryl)methylene-1-piperidinyl group; and a method of treating subjects suffering from psychotic diseases and/or disorders with 2-aminopyrimidinone derivatives substituted with a 4-arylcarbonyl-1-piperidinyl, 4-benzazolyl-1-piperidinyl, 4-benzazolyl-1-piperazinyl or 4-indolyl-1-piperidinyl, 4-benzol[b]furanyl-1-piperidinyl or 4-benzo[b]thienyl-1-piperidinyl group are also described.

Affiliated with

Also associated with

Rating

2-aminopyrimidinone derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-aminopyrimidinone derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-aminopyrimidinone derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1654071