2' and 3' - substituted cyclobutyl nucleoside analogs for...

Details 2' and 3' - substituted cyclobutyl nucleoside analogs for... 2' and 3' - substituted cyclobutyl nucleoside analogs for...

C - Chemistry, Metallurgy

07

D

C07D 239/47 (2006.01) A61K 31/513 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2590115

Provided are cyclobutyl nucleosides and methods for their use in treatment of infections including Retroviridae (including HIV), Hepadnaviridae (including HBV), or Flaviviridae (including BVDV and HCV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans.

L'invention concerne des nucléosides de cyclobutyle et des procédés relatifs à leur utilisation pour le traitement des infections, y compris l'infection par Retroviridae (dont le VIH), Hepadnaviridae (dont le VHB), ou Flaviviridae (dont le virus de la diarrhée virale des bovins (BVDV) et le VHC), ou des états liés à une prolifération cellulaire anormale, chez un hôte, y compris les animaux, et en particulier les humains.

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