C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 19/10 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2662848
The invention relates to the derivatives of general formula (I) in which: R1 is: a phenyl group or a naphthyl group, it being possible for these two groups to be optionally substituted; R2 and R3 are, independently of one another, a hydrogen atom, a (C1-C6)alkyl, (C3-C7)cycloalkyl or (C3-C7)cycloalkyl(C1-C3)alkylene group, which is optionally substituted; an optionally substituted aryl group; R4 is: a hydrogen atom, a (C1-C6)alkyl, (C3-C7)cycloalkyl or (C3-C7)cycloalkyl(C1-C3)alkylene group, which is optionally substituted; an aryl group optionally substituted with one or more substituents in the form of a base or of an addition salt with an acid.
L'invention concerne les dérivés de formule générale (I) dans laquelle : R1 représente : un groupe phényle ou un groupe naphthyle, ces deux groupes pouvant éventuellement être substitués; R2, R3 représentent, indépendamment l'un de l'autre, un atome hydrogène, un groupe (C1-C6)alkyle, (C3-C7)cycloalkyle (C3- C7)cycloalkyl(C1-C3)alkylène, éventuellement substitué; un groupe aryle éventuellement substitué; R4 représente : un atome d'hydrogène, un groupe (C1-C6)alkyle, (C3-C7)cycloalkyle (C3- C7)cycloalkyl(C1-C3)alkylène, éventuellement substitué; un groupe aryle éventuellement substitué par un ou plusieurs substituants à l'état de base ou de sel d'addition à un acide.
Almario Garcia Antonio
Lardenois Patrick
Olivier Anne
Robic
Sanofi-Aventis
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