2-aryl-pyrazolo¬4,3-c|quinolin-3-(1h and 5h)-one compounds,...

Details 2-aryl-pyrazolo¬4,3-c|quinolin-3-(1h and 5h)-one compounds,... 2-aryl-pyrazolo¬4,3-c|quinolin-3-(1h and 5h)-one compounds,...

C - Chemistry, Metallurgy

07

D

260/273.5

C07D 471/04 (2006.01) C07C 205/56 (2006.01) C07D 215/54 (2006.01) C07D 215/56 (2006.01) C07D 231/22 (2006.01) C07D 231/32 (2006.01)

Patent

CA 1148159

4-12400/CGC 893/+ Canada 2-Aryl-pyrazolo[4,3-c]quinolin-3-(1H and 5H)-one compounds, process for their preparation Abstract of the disclosure The invention concerns the compounds of the Formulae I and II Image (I) and Image (II) wherein R3 is hydrogen, lower alkyl, lower alkoxy, halogen and tri- fluoromethyl; R is phenyl which may be substituted with lower alkyl, lower alkoxy, lower alkylthio, hydroxy, one or two halogen atoms, trifluoromethyl, nitro, amino, mono-lower alkylamino, di-lower alkyl- amino, cyano, carbamoyl, mono-lower alkylcarbamoyl, di-lower alkyl- carbamoyl, and carboxy, or R is pyridyl which may be substituted by lower alkyl or halogen; R1 is hydrogen, lower alkyl, di-lower alkyl- amino-lower alkyl, and phenyl lower alkyl wherein the phenyl group may be substituted with halogen; and R2 is hydrogen and lower alkyl; their 3-hydroxy tautomers; lower alkanoyl, carbamoyl, mono- or di-lower alkylcarbamoyl derivatives of the compounds, in which R is amino- phenyl; or salts thereof. The compounds exhibit psychoactive effects. They are prepared by ringclosing a compound of the Formula Image (IV) wherein X is -NH-NH-R and Y is hydroxy or lower alkoxy,and, if desired, reacting a resulting compound with a reactive ester of an alcohol R1-OH.

354349

Affiliated with

Also associated with

Rating

2-aryl-pyrazolo¬4,3-c|quinolin-3-(1h and 5h)-one compounds,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-aryl-pyrazolo¬4,3-c|quinolin-3-(1h and 5h)-one compounds,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-aryl-pyrazolo¬4,3-c|quinolin-3-(1h and 5h)-one compounds,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-111995