2 -arylaminoquinazolines for treating proliferative diseases

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 239/84 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/10 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2727251

The invention provides novel compounds that are inhibitors of PDKI. Also provided are pharmaceutical composi-tions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or composi-tion.

L'invention concerne de nouveaux composés qui sont des inhibiteurs de PDK1. L'invention se rapporte aussi à des compositions pharmaceutiques renfermant les composés et à des procédés permettant de traiter des maladies prolifératives, telles que les cancers, à l'aide desdits composés ou desdites compositions.

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