2-arylbenzothiazoles and uses thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/12 (2006.01) A61K 31/426 (2006.01)

Patent

CA 2615420

The present invention relates to compounds of the general formula (I) and salts, prodrugs, and stereoisomers thereof, formula (I),wherein Y independently represents S, O, NR2, SO, SO2; A independently represents a fife- or six-membered aromatic carbocycle or heterocycle and wherein R1 to R20 in formula (I) represent independently of each other a variety of different substituents comprising alkyl, aryl, aralkyl, alkylaryl, heteroaryl groups and monofunctional moieties.

L'invention concerne des composés de formule générale (I), ainsi que leurs sels, promédicaments et steréoisomères, formule dans laquelle Y désigne, indépendamment, S, O, NR2, SO, SO2; A désigne, indépendamment un carbocycle ou un hétérocycle aromatique à cinq ou six chaînons, et où R1 à R20 désignent, dans la formule (I), indépendamment l'un de l'autre, une variété de différents substituants comprenant les groupes ci-après : alkyle, aryle, aralkyle, alkylaryle, hétéroaryle et des fractions monofonctionnelles.

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