2-arylimidazopyridines

Details 2-arylimidazopyridines 2-arylimidazopyridines

C - Chemistry, Metallurgy

07

D

167/231, 260/273

C07D 471/04 (2006.01) A61K 31/435 (2006.01) C07C 65/24 (2006.01) C07C 65/28 (2006.01)

Patent

CA 1294277

ABSTRACT OF THE DISCLOSURE New 2-arylimidazopyridines of the general formula I Image I wherein -A=B- is (a) -CH=N- or (b) N=CH-, Ar is a phenyl radical, which, in case (a), is substituted by one or two alkynyloxy, cyanomethoxy, carboxymethoxy, and/or alkyloxycarbonylmethoxy groups, and can be substituted by one or two additional hydroxyl, alkyloxy, alkenyloxy and/or alkynyloxy groups, or which in case (b), is substituted by one to three hydroxyl, mercapto, and/or -Z-R groups, Z is -O-, -S- or -SO- and R is alkyl, alkenyl, alkynyl, hydroxyalkyl, cyano- methyl, carboxymethyl or alkyloxycarbonylmethyl, the alkyl, alkenyl, alkynyl and hydroxyalkyl groups each having up to 5 C atoms, but wherein in case (b), the phenyl radical is only substituted by hydroxyl or methoxy groups if it has at the same time at least one other substituent differing from these, and their physiologically acceptable salts show positive inotropic effects.

506385

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