2-arylimino-2,3-dihydrothiazole derivatives, methods for...

Details 2-arylimino-2,3-dihydrothiazole derivatives, methods for... 2-arylimino-2,3-dihydrothiazole derivatives, methods for...

C - Chemistry, Metallurgy

07

D

C07D 277/42 (2006.01) A61K 31/425 (2006.01) C07D 241/00 (2006.01) C07D 277/00 (2006.01) C07D 277/38 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2434203

The invention concerns novel 2-arylimino-2,3-dihydrothiazole derivatives, the methods for preparing them and their use as medicines, in particular for treating pathological conditions or diseases wherein one (or several) somatostatin receptors are involved. Said conditions include in particular acromegaly, hypophisial adenoma or endocrinal gastroentero-pancreatic tumours including the carcinoid syndrome, and gastrointestinal bleeding.

L'invention a pour objet de nouveaux dérivés de 2-arylimino-2,3- dihydrothiazoles, leurs procédés de préparation et leur utilisation en tant que médicaments, en particulier dans le traitement des états pathologiques ou des maladies dans lesquels un(ou plusieurs) des récepteurs de la somatostatine est(sont) impliqué(s). Ces états incluent en particulier l'acromégalie, les adénomes hypophysaires ou les tumeurs gastroentéropancréatiques endocriniennes dont le syndrome carcinoïde, et les saignements gastro-intestinaux.

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