2-arylindole derivatives as npges-1 inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 209/08 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 209/10 (2006.01) C07D 209/12 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2655750

A 2-arylindole compound substituted in position 5, of formula (I): in which X, Y, Z, W, A, R and R' have the meanings given in the description, a pharmaceutical composition comprising it, and also intermediate compounds and a preparation process therefor.

L'invention porte sur un composé 2-arylindole substitué en position 5, de la formule (I), dans laquelle X, Y, Z, W, A, R et R' possèdent les significations données dans la description; sur une composition pharmaceutique renfermant ledit composé; et sur des composés intermédiaires et un procédé de préparation de ces derniers.

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