C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/50 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 409/10 (2006.01) C07D 409/12 (2006.01) C07D 417/10 (2006.01)
Patent
CA 2245755
The invention relates to IP receptor antagonists selected from the group of compounds represented by formula Image wherein R1 is a group represented by formula (A), (B) or (C): Image Image Image and other substituents as defined in the specification, and their pharmaceutically acceptable salts, crystal forms therof and pharmaceutical compositions containing them.
L'invention porte sur des antagonistes du récepteur IP, choisis dans le groupe de composés représentés par la formule Image , où R1 est un groupe représenté par la formule (A), (B) ou (C) Image Image Image , les autres substituants correspondant à la définition donnée dans la spécification; ainsi que sur leurs sels pharmacocompatibles, leurs formes cristallisées et les compositions pharmaceutiques qui en renferment.
Bley Keith Roger
Clark Robin Douglas
Jahangir Alam
Kowalczyk Bruce Andrew
Lopez-Tapia Francisco Javier
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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