2-aza-bicyclo[2.2.1]heptane derivatives

Details 2-aza-bicyclo[2.2.1]heptane derivatives 2-aza-bicyclo[2.2.1]heptane derivatives

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/427 (2006.01) A61K 31/4709 (2006.01) A61P 25/00 (2006.01) C07D 405/12 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 493/04 (2006.01) C07D 495/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2713184

The invention relates to novel 2-aza-bicy-clo[2.2.1]heptane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

L'invention concerne de nouveaux dérivés de 2-aza-bicyclo[2.2.1]heptane de formule (I), dans laquelle A, B, n et R1 sont tels que décrits dans la description, ainsi que l'utilisation de tels composés ou de sels pharmaceutiquement acceptables de tels composés en tant que médicaments, notamment en tant qu'antagonistes du récepteur d'orexine.

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