2-aza-bicyclo[3.1.0]hexane derivatives

Details 2-aza-bicyclo[3.1.0]hexane derivatives 2-aza-bicyclo[3.1.0]hexane derivatives

C - Chemistry, Metallurgy

07

D

C07D 407/12 (2006.01) A61K 31/427 (2006.01) A61P 25/00 (2006.01) C07D 407/14 (2006.01) C07D 417/14 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2669821

The invention relates to novel 2-aza-bicyclo[3.1.0]hexane derivatives of Formula (I) wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

La présente invention concerne de nouveaux dérivés 2-aza-bicyclo[3.1.0]hexane représentés par la formule (I) dans laquelle A, B, et R1 sont tels que décrits dans la description et l'utilisation de tels composés ou de sels pharmaceutiquement admis de tels composés, comme médicaments, et plus particulièrement comme antagonistes du récepteur de l'orexine.

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