2-azaergolines and 2-aza-8(or 9)- ergolines

Details 2-azaergolines and 2-aza-8(or 9)- ergolines 2-azaergolines and 2-aza-8(or 9)- ergolines

C - Chemistry, Metallurgy

07

D

260/206, 260/273

C07D 457/04 (2006.01) C07D 221/10 (2006.01) C07D 471/06 (2006.01)

Patent

CA 1107275

X-4959 -1- ABSTRACT OF THE DISCLOSURE Novel 2-azaergolines, 2-aza-8(or 9)-ergolenes, which are neuroleptic agents, are described herein. These compounds are prepared by reacting a 7-amino-6- ketobenzo[f]quinoline with a diazotization agent, e.g. sodium nitrite and a strong mineral acid, to yield the 6-keto-7-diazonium salt intermediate, followed by reduction to yield the final product.

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