A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/351 (2006.01) A61P 3/06 (2006.01) C07D 205/08 (2006.01) C07D 405/10 (2006.01) C07D 405/12 (2006.01) C07D 409/10 (2006.01) C07D 409/12 (2006.01) C07H 15/26 (2006.01)
Patent
CA 2543943
The instant invention provides novel cholesterol absorption inhibitors of Formula I and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events.
La présente invention concerne de nouveaux inhibiteurs d'absorption de cholestérol de formule (I), ainsi que les sels et les esters de ceux-ci, acceptables d'un point de vue pharmaceutique. Ces composés sont utilisés pour abaisser les taux de cholestérol plasmatique, notamment le cholestérol LDL, et pour traiter et prévenir l'athérosclérose et des maladies athéroscléreuses.
Maccoss Malcolm
Myers Robert W.
Sings Heather I.
Ujjainwalla Feroze
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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