C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/357, 260/382
C07D 311/12 (2006.01) C07D 311/16 (2006.01) C07D 407/06 (2006.01)
Patent
CA 1080237
Abstract of the Disclosure Novel 2-benzopyranone compounds of the formula Image wherein X is a 3,4,5-trimethoxybenzoyl group or a 3,4,5-trimethoxycinnamoyl group; and each R individually is selected from the group consisting of alkylamino and dialkylamino in which one carbon atom in the alkyl moiety may be replaced by an oxygen atom and one hydrogen atom may be replaced by a hytroxyl group which may in turn be esterified with a 3,4,5-trimethoxybenzoyl or 3,4,5-trimethoxycinnamoyl group; amino substituted once or twice by alkenyl, aralkyl, or cycloalkyl; or a 4- to 7- membered N-containing heterocyclic ring linked through a nitrogen atom find which contains up to 3 hereto atoms, which heterocyclic ring may be substituted by phenyl, alkyl or hydroxyalkyl, wherein the hydroxy group may be esterfied by a 3,4,5-trimetoxy benzoyl or 3,4,5-trimethoxy cinnamoyl group; or a salt of each compound with a physiologically acceptable acid; possess outstanding activity as corconary dilators. Processes for producing such compounds are also disclosed.
256404
Boltze Karl-Heinz
Jacobi Haireddin
Schwarz Helmut
Seidel Peter-Rudolf
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