2-benzoyl-imidazo(1,2-.alpha) pyridine derivatives, their...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 19/00 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2710801

Compounds of formula (I) in which: X is an optionally substituted phenyl group; R2 is an optionally substituted heterocyclic group; R1 is a hydrogen atom, a halogen, a (C1-C6)alkoxy group, a (C1-C6)alkyl group, a hydroxyl group or an amino group; R3 is a hydrogen atom, a (C1-C6)alkyl group, a halogen atom or a hydroxyl group, and R4 is a hydrogen atom or a halogen atom, in the form of a base or of an addition salt with an acid. Therapeutic use.

Composés de formule (I) dans laquelle: X représente un groupe phényle éventuellement substitué; R2 représente un groupe hétérocyclique éventuellement substitué; R1 représente un atome d'hydrogène, un halogène, un groupe (C1-C6)alcoxy, un groupe (C1-C6)alkyle, hydroxy, amino; R3 représente un atome d'hydrogène, un groupe (C1-C6)alkyle, un atome d'halogène, ou un groupe hydroxy, R4 représente un atome d'hydrogène ou un atome d'halogène, à l'état de base ou de sel d'addition à un acide. Utilisation en thérapeutique.

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