2-benzyl and 2-heteroaryl benzimidazole nmda/nr2b antagonists

A - Human Necessities – 61 – K

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Details

A61K 31/4184 (2006.01) A61K 31/4418 (2006.01) A61K 31/4439 (2006.01) C07D 235/12 (2006.01) C07D 235/18 (2006.01) C07D 401/06 (2006.01) C07D 403/08 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2389259

Novel benzimidazoles, substituted in the 2-position by substituted benzyl groups or heteroaryl groups are effective as NMDA NR2B antagonists and are useful for relieving pain.

De nouveaux benzimidazoles, substitués dans la position 2 par des groupes benzyle ou des groupes hétéroaryle substitués, sont efficaces en tant qu'antagonistes de NMDA et NR2B, et sont utiles pour soulager la douleur.

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