C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/241.5
C07D 223/04 (2006.01) C07D 223/10 (2006.01) C07D 223/12 (2006.01)
Patent
CA 1114374
Abstract of the Disclosure This invention relates to 2-benzyl-perhydroazepines of the general formula I Image (I), in which R1 is a hydrogen atom, an aliphatic or alicyclic hydrocarbon radical, a cycloalkylalkyl group or an aralkyl group, R2, R3, R4 and R5 are the same or different and signify a hydrogen atom, a halogen atom, an alkyl group, a hydroxy group, an alkoxy group, an acyloxy group, an optionally substituted amino group, a nitro group, an optionally substituted phenyl group, R1 not being methyl if R2, R3, R4 and R5 mean hydrogen, and their acid addition salts. This invention also relates to a process for the preparation of these compounds from known materials. The compounds of formula (I) and their pharmacologically compatible acid addition salts are useful in human and veterinary medicine because they produce central stimulation, an increase in vigilance, promote normal and pathologically inhibited drive of warm-blood animals. In addition some representatives display a strong analgesic action or an action which influences the blood pressure.
302270
Byk Gulden Lomberg Chemische Fabrik G.m.b.h.
Fetherstonhaugh & Co.
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