(2-carboxamido)(3-amino) thiophene compounds

Details (2-carboxamido)(3-amino) thiophene compounds (2-carboxamido)(3-amino) thiophene compounds

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/437 (2006.01) A61K 31/4436 (2006.01) A61K 31/4709 (2006.01) A61P 35/00 (2006.01) C07D 409/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2512608

Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, wherein R1 is Formula (II, III, IV, V or VI); R2 is Formula (VII, VIII, IX or X); and R3 is C0-4 alkyl, are useful in the treatment of cancer.

L'invention concerne des composés représentés par la formule (I) où R1 représente ou ; R2 représente et R3 représente C¿0-4 ?alkyle). L'invention concerne également un sel pharmaceutiquement acceptable ou un N-oxyde de ces derniers. Ces composés sont utiles dans le traitement du cancer.

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