2-cyano-3- or 4-(substituted amino) oxanilic acid derivatives

Details 2-cyano-3- or 4-(substituted amino) oxanilic acid derivatives 2-cyano-3- or 4-(substituted amino) oxanilic acid derivatives

C - Chemistry, Metallurgy

07

D

260/514.2, 260/3

C07D 295/12 (2006.01) C07D 265/26 (2006.01) C07D 295/155 (2006.01)

Patent

CA 1061356

ABSTRACT OF THE DISCLOSURE The 2-cyano-3-or 4-(substituted amino) oxanilic acid derivatives of the formula: Image in which the group Image appears in the designated 3- or 4- position and R is -H; and alkali metal; +NH4; alkyl of 1 to 6 carbon atoms, inclusive; aralkyl of 7 or 8 carbon atoms; or cycloalkyl of 5 or 6 carbon atoms; R1 is -H or alkyl of 1 to 9 carbon atoms; R2 is -H, alkyl of 1 to 9 carbon atoms or cycloalkyl of 3 to 6 carbon atoms; R1 and R3, together, with the nitrogen atom to which they are attached, are aziridinyl, azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, 4-lower alkyl-piperazinyl, morpholino or thiomorpholino; and pharmaceutically acceptable acid addition salts thereof are anti-allergic agents.

259877

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