2'-deoxy-isoquanosines, isosteric analogues and isoquanosine...

Details 2'-deoxy-isoquanosines, isosteric analogues and isoquanosine... 2'-deoxy-isoquanosines, isosteric analogues and isoquanosine...

C - Chemistry, Metallurgy

12

P

C12P 19/34 (2006.01) A61K 31/70 (2006.01) C07H 19/04 (2006.01) C07H 21/00 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2124814

2'-Deoxyisoguanosine, isosteric analogues and isoguanosine derivatives of formulae I - V, processes for their production via compounds of the general formulae a or b and reaction with aroyl isocyanates or from compounds of the general formulae VI - IX by photochemical irradiation. A further production process is the conversion of deoxyguanosines or guanosines by means of persilylation, reaction with ammonia and deamination in the 2 position. The compounds are suitable as pharmaceutical agents with antiviral efficacy.

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