2-deoxyfortimicin a, 4-n-alkyl and...

C - Chemistry – Metallurgy – 07 – D

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260/360.3, 260/3

C07D 309/14 (2006.01) C07H 15/224 (2006.01)

Patent

CA 1123843

Abstract 2-Deoxyfortimicin A, 2-deoxy-4-N-alkyl fortimicins and 2-deoxy-4-N-acyl fortimicins represented by the formula Image wherein R is selected from the group consisting of acyl, aminoacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylamino- acyl, hydroxy-substituted aminoacyl, an amino acid residue, hydroxy- acyl, loweralkyl, aminoloweralkyl, N-monoloweralkylaminoloweralkyl, hydroxyloweralkyl, N-N-diloweralkylaminoloweralkyl or hydroxy- substituted aminoloweralkyl, and the pharmaceutically acceptable salts thereof; intermediates therefor; and pharmaceutical compositions containing the compounds of this invention.

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