2-formylamino-phenylguanidines, processes for their...

C - Chemistry – Metallurgy – 07 – C

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260/468.8

C07C 279/24 (2006.01)

Patent

CA 1104154

2-Formylamino-phenylguanidine, processes for their preparation and their use as medicaments. Abstract of the Disclosure N-(2-formamidophenyl)-N',N"-bis-carbonylguani- dines bearing an optionally substituted phenoxy, phenyl- thio, phenylsulfinyl or phenylsulfonyl group in the 4- or 5-position of the 2-(formamido)-phenyl group are anthel- mintic agents. The compounds, of which N-(2-formamido-4 phenylthiophenyl)-N',N"-bis-carbomethoxyguanidine is a typical example, are prepared through the reaction of iso- thiourea-S-alkyl ether and an appropriately substituted 2- aminoformanilide. Le A 16 986 - 1 -

273557

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