2-guanidino-4-arylquinazolines as nhe-3 inhibitors

Details 2-guanidino-4-arylquinazolines as nhe-3 inhibitors 2-guanidino-4-arylquinazolines as nhe-3 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/84 (2006.01) A61K 31/517 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2406161

The invention relates to compounds of formula (I), where Ar = unsubstituted, or monosubstituted by R3, phenyl, or naphthyl; R1, R2 = independently, A, OA, Hal or CF3; R3 = A, OA, Hal, or CF3; A = 1-6C alkyl and Hal = F, Cl, Br or I and the salts and solvates thereof as NHE3 inhibitors.

L'invention concerne des composés de formule (I) dans laquelle Ar représente phényle ou naphtyle non substitué ou substitué une fois par R?3 ¿; R?1¿ et R?2¿ représentent indépendamment l'un de l'autre H, A, OA, Hal ou CF¿3 ?; R?3¿ représente A, OA, Hal ou CF¿3 ?; A représente alkyle comportant 1, 2, 3, 4, 5 ou 6 atomes de C ; Hal représente F, Cl, Br ou I. L'invention concerne également les sels et solvates de ces composés, ainsi que leur utilisation comme inhibiteurs de NHE-3.

Affiliated with

Also associated with

Rating

2-guanidino-4-arylquinazolines as nhe-3 inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-guanidino-4-arylquinazolines as nhe-3 inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-guanidino-4-arylquinazolines as nhe-3 inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1518301