2-halo-2'-deoxyadenosine treatment for histiocytosis

Details 2-halo-2'-deoxyadenosine treatment for histiocytosis 2-halo-2'-deoxyadenosine treatment for histiocytosis

A - Human Necessities

61

K

A61K 31/70 (2006.01) C07H 19/173 (2006.01)

Patent

CA 2199271

An improved method for treating histiocytosis, such as Langerhans cell histiocytosis is disclosed. In accordance with that method, a therapeutically effective amount of a 2-halo-2'-deoxyadenosine is administered to a host mammal such as a human patient having histiocytosis in an amount of about 0.5 to 0.9 mg/kg of body weight over a course of about 5 to 9 days for up to two courses.

L'invention concerne un procédé amélioré de traitement de l'histiocytose telle que l'histiocytose de la cellule de Langerhans. Selon ce procédé, on administre une dose thérapeutique efficace d'une 2-halo-2'-désoxyadenosine à un mammifère hôte tel qu'un patient humain atteint d'une histiocytose, dose comprise entre environ 0,5 et 0,9 mg/kg du poids du corps pendant une durée d'environ 5 à 9 jours renouvelable une fois.

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