(2-haloergolinyl)-n'-n'-diethylurea derivatives, process for...

C - Chemistry – Metallurgy – 07 – D

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C07D 457/12 (2006.01) C07D 457/04 (2006.01) C07D 457/06 (2006.01)

Patent

CA 1175043

ABSTRACT OF THE DISCLOSURE (2-Haloexgolinyl)-N',N'-diethylurea derivatives of Formula I (I) Image and the salts thereof, wherein R is hydrogen, alkyl of up to 6 carbon atoms, or alkenyl of up to 3 carbon atoms, X is halogen, Image is a CC-single or CC double bond, and the urea residue in the 8-position can be in the .alpha.- or .beta.-configuration, have neuropsychotropic and antihypertensive properties. As a result, they are excellently suitable for inhibition of lactation, and for treatment of Parkinson- ism, psychotic disturbances, and high blood pressure.

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