2-halogeno-oxetanocin a and phosphoric ester thereof

Details 2-halogeno-oxetanocin a and phosphoric ester thereof 2-halogeno-oxetanocin a and phosphoric ester thereof

C - Chemistry, Metallurgy

07

H

C07H 19/16 (2006.01) A61K 31/70 (2006.01) C07H 19/02 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2057432

Abstract It was found that 2-halogeno-oxetanocin A and 4'-phosphate thereof represented by the following general formula (1): (1) Image wherein X represents a halogen atom and R represents a hydrogen atom or a phosphoric acid residue Image or salts thereof exhibit a strong antiviral activity and are useful as an active ingredient of therapeutic drug for viral diseases. Further, it was also found that the compounds of this invention are characterized in that they are not inactivated by adenosine deaminase widely present in living bodies and exhibit a high residual activity.

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