C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/202, 167/220
C07D 473/00 (2006.01) A61K 31/70 (2006.01) C07H 19/04 (2006.01) C07H 19/052 (2006.01) C07H 19/056 (2006.01) C07H 19/16 (2006.01)
Patent
CA 1336903
This invention relates to certain novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives, and pharmaceutical compositions thereof, which are useful in inhibiting AdoMet-dependent transmethylation and in the treatment of patients afflicted with neoplastic or viral disease states.
613429
Edwards Michael L.
Jarvi Esa T.
Mccarthy James R.
Prakash Nellikunja J.
Stemerick David M.
Merrell Dow Pharmaceuticals (canada) Inc.
Osler Hoskin & Harcourt Llp
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