2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/00 (2006.01) A61K 31/70 (2006.01) C07H 19/04 (2006.01) C07H 19/052 (2006.01) C07H 19/056 (2006.01) C07H 19/16 (2006.01)

Patent

CA 1336903

This invention relates to certain novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives, and pharmaceutical compositions thereof, which are useful in inhibiting AdoMet-dependent transmethylation and in the treatment of patients afflicted with neoplastic or viral disease states.

613429

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