2-(hetero)aryl-substituted purin-6-ones as phosphodiesterase...

Details 2-(hetero)aryl-substituted purin-6-ones as phosphodiesterase... 2-(hetero)aryl-substituted purin-6-ones as phosphodiesterase...

C - Chemistry, Metallurgy

07

D

C07D 473/30 (2006.01) A61K 31/522 (2006.01) A61K 31/5377 (2006.01) A61P 15/10 (2006.01) A61P 15/12 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2322900

There is provided compounds of formula IA and of formula IB, (See formula IA & IB) wherein R1, R2, R3, Het1 and X have meanings given in the description, which are useful in the curative and prophylactic treatment of medical conditions for which inhibition of a cyclic guanosine 3',5'-monophosphate phosphodiesterase (e.g. cGMP PDE5) is desired.

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