2-hydrazonopropionic acid derivatives and the preparation...

Details 2-hydrazonopropionic acid derivatives and the preparation... 2-hydrazonopropionic acid derivatives and the preparation...

A - Human Necessities

61

K

260/479, 260/518

A61K 31/195 (2006.01) A61K 31/15 (2006.01) A61K 31/185 (2006.01) A61K 31/19 (2006.01)

Patent

CA 1109077

ABSTRACT OF THE DISCLOSURE New propionic acid derivatives and their process of preparation; the derivatives have the formula (I) Image (I) wherein R is a straight-chain, branched-chain or cyclic, saturated or unsaturated, aliphatic hydrocarbon radical and X is a valency bond or a straight-chain or branched-chain saturated or unsaturated, divalent aliphatic hydrocarbon radical containing up to 4 carbon atoms, with the proviso that when X is a valency bond, R is other than a saturated cycloalkyl radical: and the physiologically acceptable salts, esters and amide, thereof, and stereoisomers thereof: the new derivatives exhibit, in comparison with the corresponding hydrazines, a considerably increased hypoglycaemic action, whereas the MAO (monoamine oxidase) inhibiting action is almost completely suppressed.

309492

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