2-hydroxy-ethanesulfonate salt

Details 2-hydroxy-ethanesulfonate salt 2-hydroxy-ethanesulfonate salt

C - Chemistry, Metallurgy

07

D

C07D 453/02 (2006.01) A61K 31/439 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2733449

The invention provides (R)-1-[3-(R)-cyclohexyl-hydroxy-phenyl-methyl)-isoxazol-5-ylmethyl]-3-(3- fluorophenoxy)-1-azonia-bicyclo[2.2.2]octane 2-hydroxyeth anesulf onate, pharmaceutical compositions containing the compound and its use as a muscarinic antagonists, for the treatment of chronic obstructive pulmonary disease.

Linvention concerne le 2-hydroxy-éthanesulfonate de (R)-1-[3-(R)-cyclohexyl-hydroxy-phényl-méthyl)-isoxazol-5-ylméthyl]-3- (3-fluoro-phénoxy)-1-azonia-bicyclo[2.2.2]octane, des compositions pharmaceutiques renfermant le composé et son utilisation en tant quantagoniste muscarinique, pour le traitement de la bronchopneumopathie chronique obstructive.

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