2-hydroxy-mutilin carbamate derivatives for antibacterial use

Details 2-hydroxy-mutilin carbamate derivatives for antibacterial use 2-hydroxy-mutilin carbamate derivatives for antibacterial use

C - Chemistry, Metallurgy

07

D

C07D 239/42 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61P 31/04 (2006.01) C07D 213/81 (2006.01) C07D 277/56 (2006.01) C07D 417/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2405132

2-(S)-hydroxymutilin carbamate derivatives of formula (I), in which R1 is a 5- or 6-membered optionally substituted heteroaryl group; and R2 is vinyl or ethyl, are useful in the treatment of bacterial infections.

Ces dérivés de 2-(S)-hydroxymutiline carbamate, correspondant à la formule (I), formule dans laquelle R?1¿ représente un groupe hétéroaryle à 5 ou 6 chaînons, éventuellement substitué, et où R?2¿ représente un vinyle ou un alcool éthylique, se révèlent des plus utiles en matière de traitement d'infections bactériennes.

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