A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/551 (2006.01) A61P 1/00 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) A61P 25/30 (2006.01) A61P 31/10 (2006.01)
Patent
CA 2352611
Methods and compositions are disclosed utilizing 2-hydroxymethylolanzapine for the treatment of psychosis in humans. 2-Hydroxymethylolanzapine exhibits a lessened liability toward drug-drug interactions than olanzapine and a more predictable dosing regimen than olanzapine. 2-Hydroxymethylolanzapine is also useful for the treatment of acute mania, mild anxiety states, anxiety disorders, schizophrenia, bipolar disorder, attention deficit hyperactivity disorder, autistic disorder, excessive aggression, substance abuse, depressive signs and symptoms, tic disorder, functional bowel disorder and fungal dermatitis.
La présente invention concerne des compositions et des méthodes faisant intervenir le composé 2-hydroxyméthylolanzapine pour le traitement de la psychose chez l'homme. Le composé 2-hydroxyméthylolanzapine se caractérise par une interaction médicamenteuse moindre que l'olanzapine et autorise un schéma posologique plus prévisible que cette dernière substance. La 2-hydroxyméthylolanzapine convient également pour le traitement des pathologies suivantes : manie aiguë, états anxieux légers, schizophrénie, troubles bipolaires, hyperactivité avec déficit de l'attention, troubles de l'autisme, hyperagressivité, abus de substances psychoactives, signes et symptômes de dépression, tics, troubles intestinaux fonctionnels et mycose cutanée.
Gowling Lafleur Henderson Llp
Sepracor Inc.
LandOfFree
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