2-hydroxypropylamine aryl ester derivatives

Details 2-hydroxypropylamine aryl ester derivatives 2-hydroxypropylamine aryl ester derivatives

C - Chemistry, Metallurgy

07

D

260/474, 260/247

C07D 295/20 (2006.01) C07C 275/14 (2006.01) C07C 275/28 (2006.01) C07D 295/215 (2006.01)

Patent

CA 1201438

Abstract of the Disclosure Novel compounds of the general formula Image wherein Ar represents a substituted or unsubstituted aromatic or heterocyclic group; W represents alkylene of from 1 to about 10 carbon atoms; and B represents -NR2COR1, -NR2CONR1R3, -NR2SO2R1,-NR2SO2NR1R3, or -NR2COOR1 wherein R1, R2 and R3 may be the same or different and may be hydrogen, alkyl, alkoxyalkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, or aralkyl, except that R1 is not hydrogen when B is -NR2SO2R1 or -NR2COOR1, or R1 and R3 may together with N form a 5 to 7 membered heterocyclic group; and the pharmaceutically acceptable salts thereof. These compounds exhibit .beta.-adrenergic blocking activity and are also useful in the treatment of glaucoma.

415282

Affiliated with

Also associated with

Rating

2-hydroxypropylamine aryl ester derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-hydroxypropylamine aryl ester derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-hydroxypropylamine aryl ester derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1266604