2-indolinone derivatives as modulators of protein kinase...

Details 2-indolinone derivatives as modulators of protein kinase... 2-indolinone derivatives as modulators of protein kinase...

C - Chemistry, Metallurgy

07

D

C07D 209/34 (2006.01) C07D 207/09 (2006.01) C07D 211/02 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2289102

The present invention relates to novel 2-indolinones and physiologically acceptable salts and prodrugs thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Cette invention a trait à des 2-indolinones ainsi qu'à leurs sels et bioprécurseurs, acceptables du point de vue pharmaceutique, modulant l'activité de protéine kinases, et, partant, dont on escompte qu'ils seront efficaces en matière de prévention et de traitement de troubles cellulaires liés à la protéine kinase, du cancer notamment.

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