C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/361.2
C07D 307/78 (2006.01) C07D 295/03 (2006.01) C07D 307/82 (2006.01) C07D 307/83 (2006.01) C07D 405/04 (2006.01) C07D 413/04 (2006.01)
Patent
CA 1068288
ABSTRACT Compounds of the formula I Image or derivatives thereof [in which R1 and R2 may be the same or different and each is selected from hydrogen or an alkyl group [preferably methy], ethyl or propyl) or R1 and R2 together form an alkylene chain; M is an alkyl group (preferably methyl, ethyl or propyl); R4, R5 and R6 may be the same or different and each is selected from hydrogen, an alkyl or an alkoxy group or a halogen atom (preferably R4, R5 and R6 are all hydrogen); and R3 is hydrogen or a group R7SO2- wherein R7 is an alkyl group (notably methyl, ethyl or propyl)] are prepared by reacting the analogous compound where -OM is -NR10R11 [wherein K10 and R11 may be the same or different and each is selected from a lower alkyl group or K10 and R11 together with the nitrogen atom form a heterocyclic ring (preferably morphlino, piperidino or pyrrolidino)] with a mixture of an acid and an alkanol The products preferably have R3O- as CH3SO2O- and where R3O- is HO- this is converted to the desired group CH3SO2O- by mesylation before or after conversion or the -NR10R11 group.
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