2-lower alkyl-3-[4-alkylaminoalkyl)-oxy-benzoyl]- indolizine...

C - Chemistry – Metallurgy – 07 – D

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260/272.5

C07D 471/04 (2006.01)

Patent

CA 1195979

ABSTRACT OF THE DISCLOSURE: The present invention relates to an indolizine derivative corresponding to the general formula: Image and the pharmaceutically acceptable acid addition salts thereof, wherein: R represents a straight- or branched-chain alkyl radical having from 1 to 4 carbon atoms or a phenyl radical, R1 represents a straight- or branched-chain alkyl radical having from 1 to 6 carbon atoms, X1 represents hydrogen, chlorine, bromine, methyl or methoxy, A represents a radical of the formula: Image in which X2 represents hydrogen, chlorine, bromine, methyl or methoxy, n represents 1 or 2. A process is also provided for the preparation of the above compounds. The compounds have useful pharmacological properties; such as for the treatment of angina pectoris. 22

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