2-lower alkyl-7-substituted amino-2 or 3-cephem-4-...

Details 2-lower alkyl-7-substituted amino-2 or 3-cephem-4-... 2-lower alkyl-7-substituted amino-2 or 3-cephem-4-...

C - Chemistry, Metallurgy

07

D

260/101.5

C07D 501/20 (2006.01) C07D 277/20 (2006.01)

Patent

CA 1102307

ABSTRACT OF THE DISCLOSURE New 2-lower alkyl-7-substituted amino-2 or 3-cephem- 4-carboxylic acid compounds are provided of the formula: Image wherein R1 is (C1 to C6)alkyl, R2 is carboxy or a protected carboxy group, R3 is amino or a protected amino group, and A is carbonyl or hydroxy(C1 to C6)alkylene, and the tautomeric forms and pharmaceutically acceptable salts thereof; the new compounds have antimicrobial activity and inhibit the growth of both gram-positive and gram-negative bacteria.

281291

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