2-methyl piperazine derivatives for treatment of...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/497 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2723494

The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I). The invention also relates to (2R)-1-(3 -chloro-2-pyrazinyl)-2-methylpiperazine, hydrochloride and a process for preparing the same. Another object of the present invention is a compound of the formula (I). Another object of the present invention is a method for the treatment or prophylaxis of a serotonin-related disorder, comprising administering to a subject in need thereof an effective amount of the compound above; as well as the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.

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