2-(n-substituted piperazinyl) steroid derivatives

C - Chemistry – Metallurgy – 07 – J

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C07J 43/00 (2006.01) A61K 31/58 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2744369

Novel chemical agents of Formula I are described herein. More specifically, 2-(N-substituted piperazinyl) pregnane and 2-(N-substituted piperazinyl) androstane derivatives exhibiting cytotoxicity on a variety of cancer cell lines are disclosed herein. (I)

La présente invention concerne de nouveaux agents chimiques de Formule I. Plus spécifiquement, la présente invention concerne des dérivés de prégnane et dandrostane de type 2-(pipérazinyle N-substitué) présentant des propriétés de cytotoxicité vis-à-vis de diverses lignées cellulaires cancéreuses. (I)

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