2-naphthalens substituted quinoline compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 215/12 (2006.01) C07D 215/14 (2006.01) C07D 215/24 (2006.01) C07D 277/64 (2006.01)

Patent

CA 1267146

ABSTRACT OF THE DISCLOSURE There are disclosed compounds having the formula Image (I) wherein Y is -CH2-, -S-, -O-, or Image ; R is hydrogen or lower alkyl; A is Image R2 is hydrogen or halo; R3 is hydrogen or halo; with the proviso that when Y is -O-, A is other than 2-naphthyl; or a pharmaceutically acceptable salt thereof and their use in the treatment in the treatment of inflammatory conditions and in the treatment of leukotriene-medicated naso-bronchial obstructive passageway conditions.

519538

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