2-(.omega.-alkylaminoalkyl)-and...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/46 (2006.01) A61K 31/40 (2006.01) C07D 403/06 (2006.01) C07D 413/06 (2006.01)

Patent

CA 1240326

"2-(.omega.-alkylaminoalkyl)-and 2-(.omega.-dialkylaminoalkyl)-3-(4-X-benzyliden)-phtalimidi- nes" ABST RACT The 2-(.omega.-alkylaminoalkyl)- and 2-(.omega.-dialkylaminoalkyl)-3-(4-X-benzylidene)phta- limidines are useful as local anesthetics. For the preparation, the adduct is formed between the suitable 3-(4-X- benzylidene)phtalide and a substituted amino-alkylamine, the adduct being then reacted with acetic anhydride; the X substituent at the position 4 of the benzylidene group then can be suitably converted according to the requirements.

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