(2-oxepanylidene)methyl-triphenylphosphonium compounds

C - Chemistry – Metallurgy – 07 – F

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260/356, 260/355

C07F 9/54 (2006.01)

Patent

CA 1071641

ABSTRACT OF THE DISCLOSURE The invention provides a compound of the formula: Image wherein R stands for the radical of formula I or formula II Image Image II wherein Z stands for -CH2 or -CH2-CH2- and R4 stands for hydrogen or for an alkyl radical of 1 to 4 carbon atoms; R1, R2 and R3, which may be the same or different, each stands for an alkyl radical of 1 to 4 carbon atoms, a cycloalkyl radical of 3 to 8 carbon atoms or a phenyl radical which may be unsubstituted or substituted by one or more radicals selected from halogen, an alkyl radical of 1 to 4 carbon atoms and an alkoxy radical of 1 to 4 carbon atoms; and x? stands for a pharmacologically acceptable anion by heating a compound of the formula: Image The substituent X is preferably a halogen such as chlorine or bromine. The compounds are useful by virtue of their analgesic properties.

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